Cyrex

What is Cyrex Testing?

Cyrex offers a broad suite of laboratory test panels that evaluate how your immune system interacts with foods, environmental factors, the gut–brain barrier, and your own tissues. These panels are designed to help clinicians gain deeper insight into immune function, autoimmune risk, intestinal barrier integrity, and triggers that may be contributing to unexplained symptoms.

The foundation of Cyrex testing is The Cyrex System™ — an immunology-based testing methodology that focuses on barrier breakdown, environmental triggers, predictive autoantibodies, neuroautoantibodies, and lymphocyte subpopulations to support a more targeted diagnostic strategy.

What Cyrex Testing Can Help With

Cyrex tests are often ordered when patients present with:

• Chronic or unexplained symptoms such as fatigue, digestive issues, joint pain, skin conditions, or neurological complaints
• Suspected immune dysregulation or autoimmunity that isn’t yet diagnosed
• Food sensitivities and dietary-related immune reactions
• Environmental sensitivities or chemical immune stress
• Gut barrier dysfunction (“leaky gut”)
• Brain and nervous system immune involvement

How It Works

All Cyrex testing must be ordered by a licensed healthcare professional qualified to request high-complexity laboratory testing. Cyrex Laboratories is CLIA-certified and uses proprietary quality control systems to help ensure the accuracy and reliability of results.

Steps to get tested include:

1. Discuss concerns and goals with your clinician.
2. Your clinician reviews and selects the appropriate Cyrex test panel(s).
3. A Cyrex shipping kit and requisition form are provided by the clinician.
4. Blood is drawn and sent to Cyrex Laboratories for analysis.
5. Results are returned to your clinician for interpretation and care planning.

Cyrex Test Categories

Cyrex offers a range of specialized panel categories tailored to different clinical needs:

Immune Evaluation & Autoimmune Risk

• The Lymphocyte MAP™ — comprehensive screening of immune cell populations
• Array 5 – Multiple Autoimmune Reactivity Screen — detects predictive autoantibodies associated with multiple tissues and conditions up to years before clinical disease may develop

Gut Health & Food Reactivity

• Gut-Brain Barrier Health Screen™ — evaluates gut and neurological barrier integrity
• Array 2 – Intestinal Permeability Screen — assesses intestinal barrier function
• Array 3X / WheatBurden™, Array 4 & Array 10 — helps identify immune reactivity to wheat, gluten, and other foods

Toxic Triggers & Immune Stress

• BiomeBurden™ Test Series — evaluates immune response to microbes, yeast, and molds
• Array 11 – Chemical Immune Reactivity Screen — tests immune response to common chemical exposures

Pathogens & Specialized Reactivity

• Array 12 – Pathogen-Associated Immune Reactivity Screen — looks at immune response to pathogens linked with autoimmunity

Who Should Consider Cyrex Testing

You might explore Cyrex testing if you or your clinician are seeking answers to complex symptoms that have not been fully explained by standard labs, including:

• Persistent digestive issues or food intolerance
• Chronic fatigue, joint pain, or systemic inflammation
• Signs of autoimmunity or immune imbalance
• Unexplained neurological or cognitive complaints
• Environmental or chemical sensitivities

Your healthcare provider can help determine which specific panels are most appropriate based on your history and clinical presentation.

To request Cyrex testing or learn more about which panel is right for you, talk with your healthcare provider and review available test options together.